Search on: BONE MORPHOGENETIC PROTEIN 5 
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Descriptor English:   Bone Morphogenetic Protein 5 
Descriptor Spanish:   Proteína Morfogenética Ósea 5 
Descriptor Portuguese:   Proteína Morfogenética Óssea 5 
Synonyms English:   BMP-5  
Tree Number:   D12.644.276.954.200.500
D12.776.467.942.200.500
D23.529.942.200.500
Definition English:   A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator of the growth of CHONDROCYTES and the synthesis of cartilage matrix proteins. Evidence for its role in cartilage formation can be seen in MICE, where genetic mutations that cause loss of bone morphogenetic protein 5 function result in the formation of small malformed ears. 
History Note English:   2009(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   53132 
Unique Identifier:   D055417 

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